Intravenous immunoglobulins containing antibodies against -amyloid for the treatment of Alzheimer's disease
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منابع مشابه
Intravenous immunoglobulins containing antibodies against beta-amyloid for the treatment of Alzheimer's disease.
OBJECTIVE Active or passive immunisation can mitigate plaque pathology in murine models of Alzheimer's disease (AD). Recently, it has been shown that antibodies against beta-amyloid (Abeta) are present in human immunoglobulin preparations (IVIgG), which specifically recognise and inhibit the neurotoxic effects of Abeta. This study reports the results from a pilot study using IVIgG in patients w...
متن کاملIntravenous immunoglobulins containing antibodies against b-amyloid for the treatment of Alzheimer’s disease
R C Dodel, Y Du, C Depboylu, H Hampel, L Frölich, A Haag, U Hemmeter, S Paulsen, S J Teipel, S Brettschneider, A Spottke, C Nölker, H J Möller, X Wei, M Farlow, N Sommer, W H Oertel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....
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Spirochetes, biofilms, and innate immune system activity have all been recently found in the brains of Alzheimer’s disease patients. The mechanism and actions of those factors in producing the disease were discussed in those studies. However, neither the production nor the role of beta amyloid was included in the discussion of those studies. In this commentary, we hypothesize how the developmen...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 2004
ISSN: 0022-3050
DOI: 10.1136/jnnp.2003.033399